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At the beginning of 2022, Europe, the United States and other developed economies were constrained by the epidemic and the Russia-Ukraine conflict and other supply side constraints, which combined with the resonance of the huge amount of liquidity of funds released to cope with the impact of the epidemic, leading to high inflation, and then the major central banks started tightening monetary policies. Under the expectation of economic recession, the popularity of M&A activities tends to slow down, and the number and scale of global investment and M&A activities have decreased compared to 2021.The number of global M&As has exceeded 54000,with a total transaction amount of over 3.3 trillion US dollars. This report first analyzes the macroeconomic environment of the M&A market in 2022,with major central banks led by the Federal Reserve and the European Central Bank initiating interest rate hikes. Global economy is expected to fall into recession, weakening market's willingness and ability to make mergers and acquisitions. Secondly, from the perspective of the international M&A market, the number and scale of M&A activities in the Americas, EMEA, and Asia Pacific regions have all decreased compared with the corresponding period last year, but M&A activities in industries such as technology, financial services, internet, and biopharmaceuticals are relatively active. Finally, we will focus on the Chinese M&A market, which is still in the transitional stage from rapid development to maturity. The activities of large enterprises to further improve their competitiveness through the integration of M&A market resources are in the ascendant. Industry, information technology, and financial industries are the main industries for mergers and acquisitions in China in 2022.