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Game activities in the field of international politics and economy，superimposed wave-like technological innovations，and the impact of uncertain factors such as the COVID-19 epidemic have accelerated the restructuring of the global industrial chain. But the integrated development of industrial chain and innovation chain is its basic development direction，the industrial chain promotes the development of the innovation chain，and the innovation chain enhances the international competitiveness of the industrial chain. According to the Fourteenth Five-Year Plan for National Economic and Social Development of the People’s Republic of China and the Outline of the Long-term Goals for 2035，the basic research and original innovation capacity of the Beijing Science and Technology Innovation Center should be improved to help drive the in-depth integration of the industrial chain and innovation chain in the Beijing-Tianjin-Hebeimetropolitan region.

Large industrial gradient and difficulty in implementing scientific achievements within the region are main restraints of deep integration of industrial chain and innovation chain in Beijing-Tianjin-Hebeimetropolitan region. To solve these problems，this report，based on the theoretical basis of systematic review of the deep integration of industrial chain and innovation chain，sorts out the relevant theories of the deep integration of industrial chain and innovation chain，summarizes the main problems faced by the integration of industrial chain and innovation chain in Beijing-Tianjin-Hebei metropolitan region，and puts forward the integration path and measures from the aspects of system mechanism，key links and areas，and spatial nodes. This report consists of 2 general reports，8 Topic reports and 3 Special reports，there are 13 chapters in all.