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This book first verifies the validity of the law of preferential growth of the means of production sector from the perspective of theoretical logic and empirical analysis, and then attempts to estimate the general profit rate of 38 countries from the perspective of two major sectors, and examines the difference between countries’ general profit rate, the law of decline and its influencing factors; the requirement of obtaining the same amount of profit with the same amount of capital on the return criterion of the general profit rate, which provides us with a benchmark to see the excess profit rate of different industries, and then study the degree of monopoly in different industries. This book attempts to apply econometric analysis methods to the study of Marxist political economy. It is a preliminary attempt to strengthen the study of quantitative political economy, and it is also an effort to promote the further development of Marxist political economy.